A pale or bleach-like patch on underwear can look surprising, but the fabric may have come into contact with an ordinary household or personal care product. The mark is a color change in the material, not enough information by itself to explain when or where it happened.
One possible cause is accidental contact with laundry bleach. A small splash during cleaning, residue on a surface, or contact with another treated item can remove dye from fabric and leave a permanent lighter area. Some personal care products can create a similar effect.
Products containing hydrogen peroxide or benzoyl peroxide may transfer from skin, hands, towels, or other clothing and lighten dyed material without looking like a typical spill. To narrow down the cause, review the products used during laundry and personal care, then keep bleach and peroxide-based items away from colored fabrics.
Follow each product's label and wash hands after use. If a mark returns even after those sources are separated, avoid guessing about a health cause and seek appropriate professional guidance if there are other concerns.
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